Bisacodyl DHG

Description

BisacodylDHG

COMPOSITION:

Bisacodyl ........................................... 5 mg

Excipients q.s .................................1 tablet

(Lactose, avicel, wheat starch, magnesium stearate, talc, PVP K30, eudragit L 100, PEG 6000, titanium dioxide, Đen ferric oxide, tartrazine lake, orange E110).

DOSAGE FORM: Enteric film coated tablet.

PRESENTATION: Box of 4 blisters x 25 enteric film coated tablets.

ACTIONS:

Bisacodyl is a locally acting laxative from the triarylmethane group. Bisacodyl stimulates after hydrolysis the mucosa of the large intestine resulting in colonic peristalsis.

Bisacodyl is hydrolyzed mainly by enzymes of the enteric mucosa to tát the desacetylbisacodyl, which is absorbed and is partly eliminated in urine and bile as glucuronide. Thanks to tát bacterial separation, the active ingredient of không tính tiền diphenol is formed in the large intestine. Bisacodyl coated tablets are formulated to tát be resistant to tát gastric and small intestinal juice. This results in a main release of the drug in the colon. After oral administration, only small amounts of the drug are absorbed. Bisacodyl is metabolized in the liver and is eliminated in urine. Following the oral administration of bisacodyl, the elimination was estimated to tát be approximately 6-8 hours.

INDICATIONS:

Treatment of constipation. For bowel evacuation before and after surgery. Before to tát take an X-ray of the colon.

CONTRAINDICATIONS:

Bisacodyl should not be used by patients undergoing surgical abdominal conditions, ileus, appendicitis, rectal bleeding, gastroenteritis.

Hypersensitivity to tát any components of the drug.

PRECAUTIONS:

The tablets should not be chewed but swallowed whole. Antacids and milk products should not be given one hour after taking the tablets. Bisacodyl should not be taken on a continuous daily basis for more kêu ca one week without asking your physician.

PREGNANCY AND LACTATION:

There are no risks reported when indicated bisacodyl to tát pregnant women and nursing mothers.

EFFECTS ON ABILITY TO DRIVE AND USE MACHINES:

No documents have been reported.

INTERACTIONS:

Prolonged administration or overdose of bisacodyl can reduce the effects of potassium-sparing diuretics or potassium supplements.

- The concomitant use of bisacodyl and antacids, H2-receptor antagonists or milk products within one hour may reduce the resistance of the coating of the tablets and result in gastric irritation.

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- Bisacodyl reduces the concentrations of digoxin; sánh it should be taken 2 hours before the ingestion of digoxin.

ADVERSE EFFECTS:

Rarely: colic, nausea.

Inform your physician about any adverse effects occur during the treatment.

OVERDOSAGE:

Symptoms: lower abdominal pain accompanied with dehydration, particularly in children and the elderly.

Treatment: Absorption can be minimised or prevented by inducing vomiting or gastric lavage. Replacement of fluids and monitoring of serum potassium may be required. Administration of antispasmodics may be of value. Correction of electrolyte imbalance is especially important in the elderly and the young.

There is no specific antidote.

DOSAGE & ADMINISTRATION:

For the treatment of constipation:

Adults and children over 10 years: oral dose of 1 - 2 tablets at night. It is advisable to tát take larger doses (3 or 4 tablets) if required.

Children aged 6 - 10 years: oral dose of 1 tablet at night.

For bowel evacuation:

Adults and children over 10 years: oral dose of 2 tablets at night.

Children aged 6 - 10 years: oral doe of 1 tablet at night.

For preparing to tát take an X-ray of the colon:

Adults and children over 10 years: oral dose of 2 tablets at night, in two successive nights before taking an X-ray.

Children aged 6 - 10 years: oral dose of 1 tablet at night, in two successive nights before taking an X-ray.

Children younger kêu ca 6 years of age should not be indicated because the tablet is unable to tát be divided into small doses.