Nilibac is an oral antibiotic belonging vĩ đại the 2nd generation Cephalosporin group, which has broad-spectrum antibacterial activity against many gram-negative and positive bacteria. To learn more about the drug, please refer vĩ đại the article below.
1. What are the uses of Nilibac?
Nilibac 250 medicine has the main ingredient is Cefuroxime axetil equivalent vĩ đại Cefuroxime 250mg and Nilibac 500 is Cefuroxime 500mg. The dosage size is a film-coated tablet.
Cefuroxime is a second generation Cephalosporin antibiotic.
After oral administration of Cefuroxime axetil the drug will be hydrolyzed by esterase enzymes vĩ đại the active antibiotic, Cefuroxime. The antibacterial action of this antibiotic is due vĩ đại inhibition of bacterial cell wall synthesis after binding vĩ đại penicillin-binding protein (PBP), which disrupts cell wall (peptidoglycan) biosynthesis, ultimately causing lysis and death. bacterial cells. Cefuroxime is an antibiotic with a broad spectrum of activity against both gram-negative and gram-positive bacteria.
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2. Indications and contraindications vĩ đại the drug Nilibac
Indications: Nibibac is used for the following infections:
Acute tonsillitis and pharyngitis; Acute sinusitis. Acute otitis truyền thông. Exacerbation of chronic bronchitis, pneumonia . Urinary tract infections such as: Cystitis; Pyelonephritis; Urethritis. Uncomplicated skin and soft tissue infections. Treatment of early Lyme disease. Gonorrhea has no complications. Contraindications: Nilibac is not used in the following cases:
Hypersensitivity vĩ đại Cefuroxime axetil or vĩ đại any ingredient in the formulation. Patients with a history of hypersensitivity vĩ đại Cephalosporin antibiotics. History of severe hypersensitivity vĩ đại any other beta-lactam antibacterial agent (including penicillins, monobactams and carbapenems).
3. Usage and dosage of Nilibac
How vĩ đại use: Nilibac is taken orally, it should be taken after meals for optimal absorption and taken within a certain period of time for greater effectiveness.
Dosage: As prescribed by the doctor and you can refer vĩ đại the dose as follows:
Adults and children over 40 kg: Acute tonsillitis, cystitis, uncomplicated skin and soft tissue infections, acute sinusitis and nasopharyngitis: Take 250mg/time (1 nilibac 250 tablet) and use 2 times/day. Acute otitis truyền thông, pneumonia, exacerbation of chronic bronchitis: Take 500mg/time and 2 times/day. Treatment of Lyme disease in the early stages: Take 500mg/time (1 Nilibac 500 tablet) and take 2 times/day for 14 days (10-21 days). Uncomplicated gonorrhea: Use a single dose of 1g. Children ( 40 kg): Acute tonsillitis and pharyngitis, acute sinusitis caused by bacteria: Oral 10mg/kg (maximum 125mg) x 2 times/day. Children two years of age and older with otitis truyền thông or in more severe cases of infection, cystitis, skin and soft tissue infections uncomplicated: Oral 15mg/kg (maximum 250mg) x 2 times/day . Lyme disease: Oral 15mg/kg (maximum 250mg) x 2 times/day for 14 days (10 vĩ đại 21 days). Pyelonephritis: Oral at a dose of 15mg/kg (maximum 250mg) x 2 times/day for 10-14 days. Missed dose and overdose:
When missed dose: Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose, take your next dose as scheduled. Missing doses contributes vĩ đại a decrease in the effectiveness of the drug and an increase in the undesirable effect of drug resistance. Overdose: In case of overdose, neurological sequelae including encephalopathy, convulsions and, more seriously, coma may occur. If you accidentally overdose and develop serious side effects, immediately go vĩ đại a medical center for timely treatment.
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4. Undesirable effects of the drug Nilibac
When using Nibibac, you may experience the following undesirable effects:
Common: Candida infection caused by an overgrowth of this fungus; eosinophilia; headache, dizziness, diarrhea, nausea, abdominal pain, transient increase in liver enzyme levels. Uncommon: Positive Coomb's test, thrombocytopenia, leukopenia and sometimes severe; dermatitis, vomiting. Incidence unknown: Jaundice, urticaria, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (exocrine necrosis); pseudomembranous colitis; drug fever, serum sickness, anaphylaxis, Jarisch-Herxheimer reaction; Clostridium difficile overgrowth; hemolytic anemia. If you notice any side effects while taking this medicine, you should immediately notify a qualified doctor or pharmacist ví that it can be treated promptly.
5. Things vĩ đại note when using Nilibac
Antibiotics should only be used when there is a bacterial infection or the patient has a high chance of superinfection, avoid using the drug for the common cold or flu if there is no superinfection. Use with caution in patients with renal failure requiring dose reduction, patients with gastrointestinal diseases such as colitis. Special attention should be paid vĩ đại some side effects such as Jarisch-Herxheimer reactions, hypersensitivity reactions, pseudomembranous colitis, etc. Do not take the drug for a long time or stop taking it arbitrarily unless indicated. Pregnancy: There are no adequate data on the use of cefuroxime in pregnant women. Animal studies have shown no adverse effects with pregnancy, embryo or fetal development, delivery, or postnatal abnormality. This medicine should only be prescribed vĩ đại pregnant women if the benefits outweigh the risks. Lactation: Cefuroxime is excreted in breast milk in small quantities, but may also affect the infant. Consider stopping breastfeeding or discontinuing the drug. People who drive and operate machines: Due vĩ đại side effects such as dizziness, it may affect the ability vĩ đại drive and use machines. Use caution in this case.
6. Drug interactions
Several drug interactions with Cefuroxim have been reported, including:
Drugs that reduce stomach acid: Combination reduces the effect of Cefuroxim axetil. Cefuroxime axetil may cause an effect on the gut microbiota, leading vĩ đại lower estrogen absorption and reduced effectiveness of combined oral contraceptives. Probenecid: Significantly increased peak drug concentrations, serum concentration time and half-life of Cefuroxime. Increases the effect of the drug and also increases the risk of overdose. Oral anticoagulants: Concomitant use increases the INR. In addition, some other drugs also have the risk of drug interactions. To ensure safety and effectiveness, tell your doctor about all medications, health foods you are taking, and other medical conditions.
Storage conditions: Storage temperature below 30 degrees Celsius; Avoid light; Keep out of moisture and reach of children. Do not use the medicine after the expiry date printed on the package.
Above is information about Nilibac, antibiotics that need vĩ đại be used under indications and should only be used when sensitive bacteria are known or suspected. If there is any abnormality while taking the medicine, you should notify your doctor immediately.